A protein antigen of Mycobacterium leprae is related to a family of small heat shock proteins.
نویسندگان
چکیده
The gene encoding an immunologically important 18-kilodalton protein antigen of Mycobacterium leprae has been sequenced, and the amino acid sequence of the antigen has been deduced. The 18-kilodalton antigen is strikingly similar in size and sequence to a family of eucaryotic heat shock proteins.
منابع مشابه
Characterization of Streptomyces albus 18-kilodalton heat shock-responsive protein.
In Streptomyces albus during the heat shock response, a small heat shock protein of 18 kDa is dramatically induced. This protein was purified, and internal sequences revealed that S. albus HSP18 showed a marked homology with proteins belonging to the family of small heat shock proteins. The corresponding gene was isolated and sequenced. DNA sequence analysis confirmed that the hsp18 gene produc...
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عنوان ژورنال:
- Journal of bacteriology
دوره 170 12 شماره
صفحات -
تاریخ انتشار 1988